Validated HPTLC Methods for Quantification of Mexiletine Hydrochloride in a Pharmaceutical Formulation

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Validated Stability Indicating HPTLC Method for Determination of Cephalexin in Bulk and Pharmaceutical Formulation

A simple, specific, precise and stability-indicating high performance thin layer chromatographic method of analysis of Cephalexin, both as a bulk drug and in formulation was developed and validated. The method employed TLC (Thin Layer Chromatography) aluminum plates pre-coated with silica gel 60 F254 as the stationary phase. The solvent system consisted of Ethyl Acetate : Methanol : Ammonia (6:...

متن کامل

Validated Colorimetric Assay of Clonidine Hydrochloride from Pharmaceutical Preparations

Clonidine hydrochloride is an antihypertensive agent used for migraine prophylaxis, attention deficit hyperactivity disorder, menopausal flushing and Tourette syndrome. The quantity of the active substance in pharmaceutical preparations must be within specific limits, in agreement with the respective label claim. Therefore, the aim of this study was to establish the conditions for two spectroph...

متن کامل

Validated Colorimetric Assay of Clonidine Hydrochloride from Pharmaceutical Preparations

Clonidine hydrochloride is an antihypertensive agent used for migraine prophylaxis, attention deficit hyperactivity disorder, menopausal flushing and Tourette syndrome. The quantity of the active substance in pharmaceutical preparations must be within specific limits, in agreement with the respective label claim. Therefore, the aim of this study was to establish the conditions for two spectroph...

متن کامل

Validated Hptlc Method for Simultaneous Estimation of Metformin Hydrochloride and Sitagliptin Phosphate in Bulk Drug and Formulation

A new simple high performance thin layer chromatographic method for simultaneous determination of antidiabetic drugs, metformin hydrochloride and sitagliptin phosphate in bulk and tablet dosage form were investigated. Chromatographic separation of the drugs were performed on aluminum plates precoated with silica gel 60 F254 as the stationary phase and the solvent system consisted of acetone:met...

متن کامل

Validated HPTLC Method for Simultaneous Determination of Quinapril Hydrochloride and Hydrochlorothiazide in a Tablet Dosage Form

Quinapril hydrochloride and hydrochlorothiazide were simultaneously determined by HPTLC in pharmaceutical formulations. The drugs were separated on silica gel 60 F(254) plates using suitable combination of solvents as mobile phase. The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the suitability of methods.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of AOAC INTERNATIONAL

سال: 2010

ISSN: 1060-3271,1944-7922

DOI: 10.1093/jaoac/93.3.820